Calcium Gluconate

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Calcium Gluconate

Eltee International offers Calcium Gluconate that is an oxidation product of glucose. It is widely used for treating the deficiency of calcium and in tonic compositions. It’s a chemical compound made up of calcium and gluconic acid.

We offer Calcium Gluconate of origin China, France, Germany, United States, United Kingdom, Netherlands and Belgium. Due to its vast industrial applications in several industries, we have carved ourselves as one of the leading ImportersManufacturers, Exporters, Distributors and Suppliers of Calcium Gluconate Powder from Maharashtra, India.

Technical Specifications Of Calcium Gluconate

Calcium Gluconate
Chemical Formula (C6H11O7)2Ca·H2O
Molecular Weight 448.40
Compositional Specifications of Calcium Gluconate
Content Calcium Gluconate, when in dried form, contains 98.0∼104.0% of calcium gluconate [(C6H11O7)2Ca·H2O].
Description Calcium Gluconate is a white crystalline or granular powder without odor or taste.
Identification (1) An aqueous solution of Calcium Gluconate (1→40) shows a reaction of calcium salt in Identification.

(2) When 1 drop of ferric chloride solution is added to 1 ml of an aqueous solution of Calcium Gluconate (1→40), a dark yellow color develops.

(3) To 5 ml of warm solution of Calcium Gluconate (1→10), 0.7 ml of glacial acetic acid and 1 ml of freshly distilled phenylhydrazine are added. It is heated in a water bath for 30 minutes and cooled. When the inner wall is rubbed with a glass rod, crystals are precipitated. These crystals are collected and dissolved in 10 ml of boiling water, where small amount of activated carbon is added. After mixing by shaking, it is filtered. After cooling, the inner wall is rubbed with a glass rod to precipitate crystals. The melting point of the dried crystals should be 196~202° (decomposition).
Purity (1) Clarity of Solution: Clarity of Solution: When 1 g of Calcium Gluconate is dissolved in 20 ml of water by heating at 60°, the solution should be almost clear

(2) Chloride: When 0.3 g of Calcium Gluconate is tested for chlorides, its content should not be more than the amount that corresponds to 0.6 ml of 0.01 N hydrochloric acid.

(3) Sulfate: When 0.5 g of Calcium Gluconate is tested for sulfates, its content should not be more than the amount that corresponds to 0.5 ml of 0.01 N sulfuric acid.

(4) Arsenic: 0.25 g of Calcium Gluconate is dissolved in 20 ml of warm water, Test Solution. This Test Solution is tested for Arsenic and it should not be more than 4ppm.

(5) Heavy metals: 1 g of Calcium Gluconate is dissolved in 30 ml of water by heating. After cooling, 2 ml of dilute acetic acid is added, Test Solution. This Test Solution is tested for heavy metals and its content should not be more than 20ppm.

(6) Sucrose or reducing sugar: 10 ml of water and 2 ml of dilute hydrochloric acid are added to 0.5 g of Calcium Gluconate, which is boiled for 2 minutes. After cooling, 5 ml of sodium carbonate solution is added, which is set-aside for 5 minutes. The solution is diluted to 20 ml with water, which is then filtered. 5 ml of the filtrate is mixed with 2 ml of Fehling solution, which is boiled for 1 minute. An orange-yellow red precipitate should not form immediately. 
Loss on Drying When Calcium Gluconate is dried for 2 hours at 80°, the weight loss should not be more than 0.5%.
Assay Approximately 0.5 g of dried material is dissolved in 5 ml of dilute hydrochloric acid, where 50 ml of water, 25 ml of sodium hydroxide solution, and approximately 0.1 g 2-oxy-1-(2'-oxy-4'-sulfo-1-naphtylazo)-3-naphthoic acid are added. The resulting solution is immediately titrated with 0.05 M EDTA solution. At the end point, the red color completely disappears and the solution turns blue.

0.05 M EDTA solution 1 ml = 22.42 mg (C6H11O7)2Ca·H2O
Permitted Use Level of Calcium Gluconate Usage of Calcium Gluconate as calcium is

1. Loaf breads : not more than 1.75% 
2. Other food items : not more than 1% 
Foods for special purpose and health supplement foods are not limited by these directions.


Certificate Of Analysis

Parameter Specification Result
Description White crystal or powder, odorless, tasteless Meets the requirements
Loss on drying ≤2.0 % 0.35%
Heavy metals ≤0.002 % <0.002%
Chloride ≤0.07 % <0.07%
Sulphate ≤0.05 % <0.05%
Arsenic ≤3 ppm <2 ppm
Reducing substances ≤1.0 % <1.0 %
Assay 98.5 – 102.0 % (monohydrate) 99.30%

Applications Of Calcium Gluconate Powder

  • Hypocalcemia
  • Treatment of HF burns
  • Magnesium sulfate overdose
  • Treat low blood calcium levels
  • Hyperkalemia

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